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1.
J. health med. sci. (Print) ; 7(3): 177-182, jul.-sept. 2021. ilus, tab, graf
Article in English | LILACS | ID: biblio-1381661

ABSTRACT

Radiosurgery is a high-precision technique for delivering, in most cases, a single highly conformal dose to a stereotactically localized target. It can be indicated for small intracranial injury treatment, using either multiple sources of 60Co (γ rays) or high energy photon beams produced by linear accelerators. In order to minimize the impact of inaccurate localization of the target or dose delivery, a rigorous Quality Assurance (QA) program must be enforced, which should include an independent auditing system. This work proposes a simple and reliable postal QA phantom to be used as an independent evaluation. In it two important parameters were verified such as, the dosimetric precision of the planning system, by comparing the absorbed doses measured in the target volume using different dosimeters (ionization chamber, films, thermoluminescent dosimeters and L-alanine dosimeters) all calibrated against a small volume ion chamber. The exact positioning of the target volume was localized using air spaces and small steel spheres to find the appropriate target coordinates. The head phantom and the instruction sheets were extensively tested and sent by mail to selected institutions. The overall results were very encouraging and suggest that the proposed phantom may be used as a postal system as part of an independent QA tool in radiosurgery.


La radiocirugía es una técnica de alta precisión para administrar, en la mayoría de los casos, una sola dosis altamente conformada en un objetivo localizado estereotípicamente. Puede estar indicado para el tratamiento de pequeñas lesiones intracraneales, utilizando múltiples fuentes de 60Co (rayos γ) o haces de fotones de alta energía producidos por aceleradores lineales. Con el fin de minimizar el impacto de la ubicación inexacta de la administración de la meta o de la dosis, se debe aplicar un riguroso programa de control de calidad (QA), que debe incluir un sistema de auditoría independiente. Este documento propone un fantoma postal de control de calidad simple y fiable que se utilizará como evaluación independiente. Se verificó dos parámetros importantes, como la precisión dosimétrica del sistema de planificación, comparando las dosis absorbidas medidas en el volumen objetivo mediante diferentes dosis (cámara de ionización, películas, dosímetros Termoluminiscentes y dosímetros de L-alanina) todos calibrados con una pequeña cámara de iones de volumen. El posicionamiento exacto del volumen objetivo se localizó utilizando espacios aéreos y pequeñas esferas de acero para encontrar las coordenadas de destino adecuadas. El fantoma principal y las hojas de instrucciones fueron ampliamente probados y enviados por correo a instituciones seleccionadas. Los resultados generales fueron muy alentadores y sugieren que el fantoma propuesto puede utilizarse como sistema postal como parte de una herramienta independiente de control de calidad en radiocirugía.


Subject(s)
Humans , Brain Neoplasms/therapy , Intracranial Arteriovenous Malformations/therapy , Radiosurgery/methods , Postal Service , Quality Control , Radiometry , Radiosurgery/adverse effects
2.
Arq. bras. neurocir ; 37(3): 167-173, 2018.
Article in English | LILACS | ID: biblio-1362853

ABSTRACT

Introduction The city of Passo Fundo, in the north of the Rio Grande do Sul state, has been standing out in the health care field for many years. The state has become a reference in endovascular interventional neuroradiology. We will cover 10 years of experience in this area and divide our observations in 3 parts: cerebral angiograms (part I), carotid angioplasties (part II) and intracranial aneurysms (part III). The goal of part I is to statistically assess the cerebral angiograms, their indications, risks and complications, as well as to do a technical review. Materials and Methods A retrospective study from 2005 to 2015 with a total of 5,567 interventional neuroradiology procedures performed. A total of 4,114 angiograms, 639 embolizations of intracranial aneurysms, 414 carotid angioplasties, 143 embolizations of cerebral arteriovenous malformations, 32 embolizations of dural arteriovenous fistulas, 102 cerebral vasospasm treatments, 21 treatments of epistaxis, 36 embolizations of craniocervical tumor, 25 thrombolysis of ischemic stroke, 18 vertebroplasties and 13 embolizations of arteriovenous malformations of the face. Results A total of 4,084 procedures performed, 21,811 vessels studied, average vase 7.62/2.82 vessel and patient/procedure. Of these, 2,536 were diagnostic procedures and 1,548 angiographic controls. Of the total, 1,188 patients received only an angiogram, 27.14% of which were therapeutic procedures. We obtained a total of 3.89% complications: 2.33% reflection vasovagal, 0.56% allergic skin reaction, anaphylactic shock 0.07%, 0.27% femoral hematoma, 0.26% transient neurological deficit, 0.12% permanent neurological deficit and no case of death. Conclusion Cerebral angiography in adults, children and infants is a safe procedure with low risk of permanent neurological complications.


Subject(s)
Cerebral Angiography/adverse effects , Cerebral Angiography/statistics & numerical data , Intracranial Arteriovenous Malformations/therapy , Cardiology Service, Hospital/history , Angioplasty/statistics & numerical data , Endovascular Procedures/statistics & numerical data , Intracranial Aneurysm/therapy , Medical Records , Prospective Studies , Retrospective Studies , Data Interpretation, Statistical , Embolization, Therapeutic , Magnetic Resonance Imaging, Interventional/methods
3.
Arq. bras. neurocir ; 33(4): 289-294, dez. 2014. tab, ilus
Article in Portuguese | LILACS | ID: lil-782244

ABSTRACT

Objetivo: Avaliar o perfil epidemiológico dos pacientes atendidos na Unidade de Neurocirurgia do Hospital de Base do Distrito Federal (HBDF), unidade de referência de doenças cerebrovasculares no Distrito Federal, bem como os métodos multidisciplinares de tratamento utilizados e a evolução clínica. Métodos: Realizou-se a análise retrospectiva de 42 pacientes portadores de malformações arteriovenosas (MAV) encefálicas admitidos no Serviço de Neurocirurgia do HBDF entre agosto de 2007 e janeiro de 2012, tratados conservadoramente ou submetidos a algum tipo de intervenção:microcirurgia intracraniana, embolização, técnica combinada ou radiocirurgia. Resultados: A distribuição por gênero perfez uma relação de 1,1:1,0 (masculino:feminino). Houve predomínio da localização supratentorial (85%, 36/42). Conforme a Escala de Spetzler-Martin (ESM), evidenciou-se predomínio de graus intermediários (graus II, III e IV), totalizando 96% (40/42). Dez pacientes (24%, 10/42) foram submetidos a tratamento cirúrgico convencional, 22 pacientes (52%, 22/42) à embolização (tratamento endovascular), 1 paciente (2,38%, 1/42) a tratamento combinado (endovascular e cirurgia), 1 (2,38%, 1/42) à radiocirurgia e 8 pacientes (19,05%, 8/42) foram tratados conservadoramente. A evolução clínica caracterizada pela Escala Modificada de Rankin (EMR) mostrou semelhança estatística em relação aos diversos tratamentos estabelecidos. Conclusão: As MAVs são lesões congênitas que, apesar de baixa prevalência, são alvo importante de estudo, por acometer principalmente adultos jovens e em idade produtiva. Este estudo, realizado em um centro de referência do Distrito Federal, evidencia característicasdemográficas peculiares dessas lesões, que são compatíveis com dados prévios da literatura e mostra que a abordagem terapêutica multidisciplinar é essencial para seu correto tratamento.


Objective: To assess the epidemiological profile of patients treated in the Neurosurgery Unit of the Hospital de Base of the Federal District (HBDF) reference unit of cerebrovascular diseases in the Federal District, as well as multidisciplinary treatment methods used and the clinical outcome. Methods: We performed a retrospective analysis of 42 patients with arteriovenous malformations (AVMs) in the brain admitted at Neurosurgery Service of HBDF between August 2007 and January 2012, treated conservatively or undergoing some type of intervention: intracranial microsurgery, embolization, combined technique or radiosurgery. Results: The gender distribution amounted a ratio of 1.1:1.0 (male:female). Predominated supratentorial localization (85%, 36/42). According to the Spetzler-Martin Scale (ESM), we observed a predominance of intermediate grades (grades II, III and IV) totaling 96% (40/42). Ten patients (24%, 10/42) were subjected to conventional surgical treatment, 22 patients (52%, 22/42) to embolization (endovascular treatment), 1 patient (2.38%, 1/42) the combined treatment (endovascular and surgery), 1 (2.38%, 1/42) radiosurgery and 8 patients (19.05% 8/42) were treated conservatively. The clinical evolution characterized by the modified Rankin Scale (EMR) showed statistical similarity with respect to several established treatments. Conclusion: The AVMs are congenital lesions that despite low prevalence are important target of study, since it affects mostly young adults and working age. This study, conducted in a referral center in the Federal District, shows peculiar demographic characteristics of these lesions, which are consistent with previous literature data and shows that the multidisciplinary therapeutic approach is essential for its proper treatment.


Subject(s)
Humans , Male , Female , Adult , Intracranial Arteriovenous Malformations/epidemiology , Intracranial Arteriovenous Malformations/surgery , Intracranial Arteriovenous Malformations/therapy
4.
Rev. chil. dermatol ; 30(2): 177-179, 2014. ilus
Article in Spanish | LILACS | ID: biblio-835939

ABSTRACT

En la actualidad, los procedimientos de radiología intervencional intracraneanos son cada vez más frecuentes. Sin embargo, la exposición a altas dosis de radiación durante la fluoroscopía puede inducir a complicaciones cutáneas como la alopecia transitoria post embolización, forma peculiar de radiodermatitis que afecta a las regiones del cuero cabelludo que reciben dosis más altas de radiación durante el proceso de embolización. El cuadro clínico se caracteriza por alopecia completa, no cicatricial, en parches con bordes bien delimitados y formas peculiares(rectángulos, círculos superpuestos), generalmente de localización occipital o en región temporo-parietal. Ocurre en promedio 2 a 4 semanas después del procedimiento endovascular, con repoblación del área alopécica a partir de las 4 a 5 semanas. Es de buen pronóstico y no requiere tratamiento específico. Es importante conocer este cuadro para poder orientar adecuadamente a los pacientes y alertar respecto a la incidencia de efectos adversos de la radiación terapéutica.


In the present, the neuroradiological procedures are more frequent. However, exposure to radiation can conduce to dermatological complication as transient alopecia after embolization, rare form of radiodermatitis that affect the areas of the scalp that receive highest doses of radiation. The clinical presentation is characterized by a complete alopecia, without any signs of inflammation of the scalp, with sharply defined patches in rare forms (rectangular, overlapped circles), generally located on occipital or temporo-parietal region. This phenomenon starts after 2 or 4 weeks since endovascular procedure, with hair re-growth after 4 or 5 weeks. It has good prognosis and no specific treatment is required. It is important to recognize this condition, in order to give adequate information to patients and warn about the incidence of adverse effects of therapeutic radiation.


Subject(s)
Humans , Male , Adult , Alopecia/etiology , Embolization, Therapeutic , Fluoroscopy/adverse effects , Radiodermatitis/etiology , Alopecia/therapy , Scalp/radiation effects , Intracranial Arteriovenous Malformations/therapy , Prognosis , Radiation Injuries/etiology
5.
Arq. bras. neurocir ; 32(1)mar. 2013. ilus
Article in Portuguese | LILACS | ID: lil-677811

ABSTRACT

As anomalias do desenvolvimento venoso (DVA) são as malformações vasculares cerebrais mais frequentes, tendo geralmente um curso benigno, e podem estar acompanhando os cavernomas. Atualmente, são mais diagnosticadas por causa dos métodos de diagnósticos por imagem que existem, como a tomografia computadorizada e, sobretudo, a ressonância magnética nuclear. Este artigo revisa as DAV em geral e as relacionadas com os cavernomas. Os artigos foram buscados na base de dados PubMed, em publicações desde 1995 a junho de 2012, usando como filtros as expressões ?anomalias do desenvolvimento venoso e malformações cavernosas? e ?anomalias venosas cerebrais e malformações cavernosas?; a pesquisa foi limitada a artigos em idioma inglês e relacionados a humanos. As sessões de referência de artigos e revisões recentes foram revisadas e os artigos pertinentes foram recuperados no formato resumo; os manuscritos em texto completo foram obtidos subsequentemente para todos os artigos originais aplicados à revisão em curso...


Developmental venous anomalies (DAV) are the most common brain vascular malformations usually, having a benign course and may be following the cavernomas. They are more diagnosed recently due to diagnostic imaging methods that exist, such as computed tomography and nuclear magnetic resonance. This article reviews the DAV in general and those relating to cavernomas. The PubMed database was searched for publications from 1995 through June 2012 using the mesh terms ?anomalies venous cerebral, development venous and cavernous malformation?, ?anomaly venous cerebral and cavernous malformation?. The search was limited to articles in the English language and related to humans subjects. Reference sections of recent articles and reviews were reviewed and pertinent articles were retrieved in the abstract format, full text manuscripts were subsequently obtained for all original articles applicable to the current review...


Subject(s)
Humans , Hemangioma, Cavernous , Magnetic Resonance Imaging , Intracranial Arteriovenous Malformations/diagnosis , Intracranial Arteriovenous Malformations/therapy
9.
Arq. bras. neurocir ; 27(4): 117-121, dez. 2008. ilus
Article in Portuguese | LILACS | ID: lil-551092

ABSTRACT

O autor classifica e discute as possibilidades de variações hemodinâmicas que ocorrem após a remoção parcial de um angioma, em relação ao nidus residual. O estudo é realizado utilizando-se os conceitos de pressão hidrostática arterial e venosa, pressão hidrostática do nidus, pressão transmural e gradiente pressórico, dentro da hidráulica e dinâmica dos fluidos, mas de maneira simplificada e objetiva.


Subject(s)
Hemodynamics , Hydrostatic Pressure , Intracranial Arteriovenous Malformations/surgery , Intracranial Arteriovenous Malformations/radiotherapy , Intracranial Arteriovenous Malformations/therapy , Cerebrovascular Circulation
10.
Arq. neuropsiquiatr ; 66(4): 795-799, dez. 2008. ilus, tab
Article in English | LILACS | ID: lil-500556

ABSTRACT

OBJECTIVE: Multiple cerebral cavernous malformation (CCM) is the hallmark of familial presentation of cavernous malformation in the brain. We describe an ongoing Familial Cerebral Cavernous Malformation Project in the Rio de Janeiro state showing genetic profile and the pattern of emergent neuroimaging findings of this particular population besides a review of the updated recommendations for management of familial CCM versus patients harboring sporadic lesions. METHOD: Four families of our cohort of 9 families were genetically mapped showing mutational profile linked to CCM1. The neuroimaging paradigm was shifted from T2*gradient-echo (GRE) sequence to susceptibility weighting MR phase imaging (SWI). RESULTS: Only two index cases were subjected to surgery. There was no surgical intervention in any of the kindreds of our entire cohort of 9 families of our Neurovascular Program within seven years of follow-up. The genetic sequencing for mutacional profile in four of these families has demonstrated only CCM1 gene affected. Our management of the familial CCM is according to the review of the literature recommendations. CONCLUSIONS: The Project of Familial Cerebral Cavernous Malformations of Rio de Janeiro detected mutations of the gene CCM1 in the first four families studied. Familial cavernous malformation are to be settled apart from the more common sporadic lesion. A set of recommendations was searched for in the literature in order to deal with these specific patients and kindreds.


OBJETIVOS: A apresentação de malformação cavernosa cerebral (CCM) através de múltiplas lesões cerebrais é a marca da forma familiar da doença. Os autores descrevem o Projeto Malformação Cavernosa Cerebral Familiar, em andamento no Rio de Janeiro, demonstrando o perfil genético e o padrão atual de achados neurorradiológicos dessa população específica e uma revisão das recomendações atuais para o manuseio e tratamento dos portadores dessa forma da doença versus os pacientes com malformação cavernosa cerebral esporádica. MÉTODO: Quatro familias de nossa coorte de 9 familias foram completamente mapeadas geneticamente e demonstraram padrão mutacional sempre ligado ao gene CCM1. O paradigma de neurimagens dessa população foi mudado para a seqüência de susceptibility weighting MR phase imaging (SWI) em substituição à seqüência T2*gradient-echo (GRE). RESULTADOS: Apenas 2 casos indices foram submetidos à ressecção cirúrgica. Não houve intervenção cirúrgica em nenhum outro parente de toda a coorte de 9 familias no período de sete anos de acompanhamento. O sequenciamento genético em busca do perfil mutacional foi completado em 4 familias demonstrando o acometimento do gene CCM1 em todas. O manuseio e tratamento de nossa população de malformação cavernosa cerebral familiar está de acordo com a revisão feita sobre recomendações da literatura. CONCLUSÃO: O Projeto Malformação Cavernosa Cerebral Familiar detectou mutações do gene CCM1 nas primeiras quatro famílias estudadas. Os portadores dessa forma de malformação cavernosa cerebral da doença devem ser considerados à parte na rotina de avaliação e tratamento em relação à forma esporádica da doença. As recomendações foram buscadas na literature para nortear o manuseio dessa população específica.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Germ-Line Mutation/genetics , Intracranial Arteriovenous Malformations/genetics , Microtubule-Associated Proteins/genetics , Proto-Oncogene Proteins/genetics , Cohort Studies , Family , Intracranial Arteriovenous Malformations/therapy , Magnetic Resonance Imaging , Phenotype
11.
Arq. bras. neurocir ; 27(3): 90-95, set. 2008. tab
Article in Portuguese | LILACS | ID: lil-551106

ABSTRACT

É feita revisão da literatura sobre malformações arteriovenosas(MAV)encefálicas. MAV são anomalias morfológicas neurovasculares caracterizadas por comunicação direta entre artérias e veias , sem interposição do leito capilar, portanto sem resistência ao fluxo sanguíneo. Morfologicamente, MAV possuem três componentes distintos:aferências, nidus e eferências.As aferências incluem vasos originados de quaisquer artérias intra ou extracranianas que nutrem as MAV.O nidus corresponde a um enovelado complexo de artérias e veias anormais,unidas por uma ou mais fístulas além de calcificações e aneurismas intranidais. As eferências constituem as drenagens venosas, que podem ser superficial,profunda ou mista.Acidentes vasculares encefálicos(AVE)hemorrágicos são as manifestações mais comuns,ocorrendo em aproximadamente 50 por cento dos casos.O tratamento de MAV pode ser microcirurgia,embolização endovascular,radiocirúrgico estereotáxico,conservador ou multidisciplinar.Ressecção cirúrgica completa de MAV é considerada a melhor opção de tratamento,eliminando risco de futura hemorragia.Apesar do desenvolvimento tecnológico na área de neurocirurgia endovascular nas últimas décadas, a fisiopatologia de MAV e sua história natural ainda não estão bem esclarecidas.O tratamento representa um grande desafio.Acreditamos que estudos sobre complexidade arquitetônica e hemodinâmica de MAV são necessários a fim de estabelecer fatores de risco e prognósticos,melhorando os resultados do tratamento.


Subject(s)
Humans , Intracranial Arteriovenous Malformations/classification , Intracranial Arteriovenous Malformations/diagnosis , Intracranial Arteriovenous Malformations/epidemiology , Intracranial Arteriovenous Malformations/etiology , Intracranial Arteriovenous Malformations/history , Intracranial Arteriovenous Malformations/therapy
12.
P. R. health sci. j ; 27(1): 27-33, Mar. 2008.
Article in English | LILACS | ID: lil-491634

ABSTRACT

BACKGROUND: Pre- and postoperative evaluation of the pediatric patient with a cerebrovascular malformation can be cumbersome. This may be due to several factors, including age and ability to verbalize. Functional evaluation scales have been devised, yet application to a retrospective study, where information can be limited, may not be possible. Simpler scales, serving the purpose of functional description and categorization would be beneficial in these cases. METHODS: Between December 1997 and December 2003, 24 patients between the ages of 4 months to 17 years old underwent endovascular treatment for cerebrovascular lesions at our institution. The majority of the arteriovenous malformation cases underwent further radiosurgical treatment. Mean follow-up period from the time of the last endovascular or radiosurgical intervention was 22 months. A pediatric modification of the Rankin Disability Scale was used for evaluation of pre-procedural and post-procedural functional status. RESULTS: Combined embolization/radiosurgical approach had 4% mortality and 4% morbidity rates. This combined technique achieved a 46% cure in a variety of pediatric vascular anomalies. Overall improvement in disability using the pediatric modification of the Rankin Scale was noted for all of the cases, and a tendency for improvement was noted in the arteriovenous malformation subgroup though not statistically significant, p = 0.0547. CONCLUSIONS: These results indicate that a pediatric modification of the Rankin Disability Scale can be used for functional evaluation in this population. Although other functional evaluation scales are available and validated, using a Rankin Disability Scale modification is straightforward, and it can provide functional categorization in retrospective studies.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Embolization, Therapeutic , Intracranial Arteriovenous Malformations/therapy , Blood Vessels/abnormalities , Radiosurgery , Retrospective Studies
14.
Arq. neuropsiquiatr ; 64(3a): 681-685, set. 2006. ilus
Article in Spanish, English | LILACS | ID: lil-435613

ABSTRACT

OBJETIVO: Mostrar dos casos de oclusión espontánea de remanente malformativo previamente embolizado y analizar sus probables causas. MÉTODO: Revisión retrospectiva de pacientes con malformaciones arteriovenosas cerebrales (MAV) embolizadas entre Enero de 1999 y Agosto de 2005 en nuestra institución y análisis de dos casos de oclusión de MAV remanentes. RESULTADOS: Se presentan dos casos de MAV tratadas por vía endovascular, con remanentes del nido malformativo post-embolización, que posteriormente en controles angiográficos presentan desaparición completa de las lesiones sin mediar otro tratamiento. CONCLUSION: La oclusión espontánea de un remanente arteriovenoso es un hecho infrecuente. Se discuten diversos mecanismos relacionados.


OBJECTIVE: To report two cases of spontaneous occlusion of residual malformations that had previously been embolized and to analyze their probable causes. METHOD: Retrospective review of patients with embolized arteriovenous malformations (AVMs) between January 1999 and August 2005 in our institution and analysis of two cases of occlusion in residual AVMs. RESULTS: Two cases of AVMs that received endovascular treatment and had post-embolization residual nidus malformation, which in later angiographic controls showed a complete disappearance of the lesions without other treatment. CONCLUSION: The spontaneous occlusion of residual arteriovenous malformations is an infrequent occurrence. Several related mechanisms are discussed.


Subject(s)
Humans , Male , Female , Adult , Intracranial Arteriovenous Malformations/therapy , Cerebral Angiography , Embolization, Therapeutic , Follow-Up Studies , Intracranial Arteriovenous Malformations , Remission, Spontaneous , Retrospective Studies
15.
Repert. med. cir ; 15(4): 209-211, 2006. ilus
Article in Spanish | LILACS, COLNAL | ID: lil-523266

ABSTRACT

Se presenta el caso de una paciente de sexo femenino de 20 meses de edad que consultó al servicio de urgencias pediátricas por cuadro de pérdida súbita y progresiva de la fuerza del hemicuerpo izquierdo, asociada con episodio convulsivo, pérdida del conocimiento de cerca de 15 segundos, astenia, adinamia, irritabilidad y somnolencia. Niega trauma craneoencefálico. La presentación de este caso y su estudio posterior obliga a la revisión de las causas más frecuentes de cuadros convulsivos en niños, síndromes hemipléjicos y hemiparéticos, con el fin de enfocar un buen diagnóstico y diseñar un plan de manejo adecuado enfocado hacia las malformaciones vasculares cerebrales o cerebelosas.


Subject(s)
Humans , Female , Infant , Arteriovenous Fistula/diagnosis , Arteriovenous Fistula/therapy , Stroke/diagnosis , Stroke/therapy , Intracranial Arteriovenous Malformations/diagnosis , Intracranial Arteriovenous Malformations/therapy
16.
Arq. neuropsiquiatr ; 63(3A): 605-613, set. 2005. ilus, tab
Article in English | LILACS | ID: lil-409042

ABSTRACT

O material utilizado consistiu de 93 pacientes portadores de malformações arteriovenosas durais (MAVDs) estudados retrospectivamente em relação ao sucesso e ao fracasso terapêutico submetidos aos métodos neurocirúrgico ou endovascular ou, ainda, combinação entre ambos, em que a doença se localizou nas regiões do seio cavernoso, do seio sagital superior, do seio transverso-sigmóide, da fossa anterior e do tentório. As conclusões foram as seguintes: o tratamento das MAVDs deve ser indicado pelo neurorradiologista intervencionista e pelo neurocirurgião, conjuntamente; as MAVDs do seio transverso-sigmóide foram melhor tratadas através do método combinado; as MAVDs do tentório foram melhor tratadas através do método combinado; as MAVDs do seio sagital superior tratadas por método endovascular asseguraram apenas 50% de sucesso terapêutico; as MAVDs do seio cavernoso são melhor tratadas por método endovascular empregando-se a via transvenosa quando comparadas com a via transarterial.


Subject(s)
Humans , Dura Mater/blood supply , Embolization, Therapeutic/methods , Intracranial Arteriovenous Malformations/therapy , Neurosurgical Procedures/methods , Cerebral Angiography , Combined Modality Therapy , Intracranial Arteriovenous Malformations , Intracranial Arteriovenous Malformations/surgery , Retrospective Studies , Treatment Outcome
17.
Arq. neuropsiquiatr ; 63(1): 34-39, Mar. 2005. tab, graf
Article in English | LILACS | ID: lil-398787

ABSTRACT

OBJETIVO: Avaliar o papel deste procedimento na prevenção de hemorragia em casos de malformação arteriovenosa (MAV) cerebrais. MÉTODO: Entre 1992 e 2000, estudamos 104 pacientes submetidos a embolização como tratamento principal. Os pacientes foram seguidos até a ocorrência de hemorragia ou morte. RESULTADOS: O período de seguimento variou de 1,6 mês a 8 anos. As apresentações mais freqüentes foram hemorragia (50%) e convulsões (38%). Além disso, 40% das lesões eram pequenas (<30 mm); 56% eram médias (30-60 mm). O grau de obliteração foi <1/3 em 11% dos casos; 1/3 a <2/3 em 49%; >2/3 em 36%; completa em 5%. O risco de morte foi 1%/ano, e de sangramento, 5,4%/ano. Apresentação com hemorragia e baixo grau de obliteração foram os principais fatores associados com hemorragia. CONCLUSÃO: A embolização em MAVs cerebrais confere proteção limitada contra hemorragia, com graus de obliteração abaixo de 2/3. Apresentação com hemorragia é o principal fator preditivo de hemorragia.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Embolization, Therapeutic , Enbucrilate/therapeutic use , Intracranial Arteriovenous Malformations/therapy , Intracranial Hemorrhages/prevention & control , Follow-Up Studies , Risk Factors , Treatment Outcome
18.
Rev. chil. neuro-psiquiatr ; 42(3): 219-222, jul. 2004.
Article in Spanish | LILACS | ID: lil-415501

ABSTRACT

Dural arteriovenous fistulas are direct arteriovenous connections within the duramater either in the cranial or spinal region. They account for 10 to 15 percent of all intracranial arteriovenous malformations and they have been consistently reported since forty years. The clinical picture is variable with mild symptoms as tinnitus or secondary to ocular venous congestion, or severe ones, like neurologic symptoms or hemorrhage. They can present at any age but most of the patients are over 50 years old. The anatomy of this malformation is variable and sometimes difficult. Natural history is not completely known, therefore the best treatment is still a matter of debate. In order to achieve a favorable treatment, many publications have been focused in the classification of these malformations based on a relation between the anatomy and the natural history.


Subject(s)
Humans , Dura Mater/blood supply , Arteriovenous Fistula/classification , Arteriovenous Fistula/therapy , Intracranial Arteriovenous Malformations/therapy , Spinal Cord/pathology , Intracranial Arteriovenous Malformations/complications
19.
Rev. méd. Chile ; 132(4): 489-492, abr. 2004. ilus
Article in Spanish | LILACS | ID: lil-362915

ABSTRACT

Arterial embolization with cyanoacrylate is commonly used for the treatment of arteriovenous malformations. We report the case of a 40 years old man who four days after an embolization with cyanoacrylate, begins with cough, bloody sputum, and right hemithorax pleuritic pain. Pulmonary embolism was confirmed with chest X ray, CT scan and scyntigraphy. The patient received anticoagulation, with adequate response. The most common complications of cerebral embolization are related to central nervous system and pulmonary embolism is exceptional. Considering the high number of embolization procedures done nowadays, this complication must be borne in mind.


Subject(s)
Humans , Male , Cyanoacrylates/therapeutic use , Pulmonary Embolism/complications , Pulmonary Embolism/etiology , Pulmonary Embolism/therapy , Embolization, Therapeutic/adverse effects , Intracranial Arteriovenous Malformations/therapy , Intracranial Embolism , Pulmonary Embolism
20.
Rev. chil. ultrason ; 7(1): 21-24, 2004. ilus
Article in Spanish | LILACS | ID: lil-401332

ABSTRACT

Presentamos el caso clínico de un recién nacido de 35 semanas de gestación con sospecha prenatal de un tumor cerebral. El cuadro clínico del recién nacido orientó hacia una malformación arteriovenosa intracraneal lo que se demostró mediante ultrasonografía con Doppler color efectuada en la UTI neonatal. Se destaca la buena correlación diagnóstica con la arteriografía cerebral efectuada por cateterismo femoral que precisó la existencia de un fístula dural gigante, presentando los buenos resultados del tratamiento mediante embolización con microcoils, que permitió la sobrevida del niño con mínima secuela, a los dos años de seguimiento.


Subject(s)
Humans , Infant, Newborn , Embolization, Therapeutic , Arterio-Arterial Fistula/diagnosis , Arteriovenous Fistula/therapy , Intracranial Arteriovenous Malformations/diagnosis , Intracranial Arteriovenous Malformations/therapy , Ultrasonography, Doppler, Color
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